Self-reported recurrent pain and medicine use among 15- year-olds: Results from the HBSC Italian study
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Keywords

recurrent complaints
adolescents
medicine use

Abstract

Background: The prevalence of adolescent pain varies considerably across epidemiological studies, and little information is available on pain-related behaviours among adolescents, including medicine use. The aims of this study were: (1) to examine the prevalence of recurrent pain among 15-year-old adolescents in Italy; (2) to investigate the association between recurrent pain and medicine use among boys and girls; and (3) to evaluate the consistency of these associations across regions.

Methods: The World Health Organization (WHO) collaborative International Health Behaviour in School-aged Children 2013/2014 study collected self-reported data on pain and medicine use from 13611 15-year-old adolescents in 21 Italian regions. We used multi-level multivariate logistic regression, stratified by gender, to analyse the association between recurrent pain and medicine use for headache, stomachache, nervousness and difficulties in getting to sleep.

Results: On average, across all regions, almost 45% of adolescents reported recurrent headache, more than 30% reported recurrent backache and approximately 30% reported recurrent stomachache. Although the prevalence of both pain and medicine use was much higher among girls, the association between pain and medicine use was similarly strong in adolescents of both genders. Adolescents with recurrent pain proved more likely to use medicines also for non-corresponding pain, nervousness and difficulties in getting to sleep. The association between recurrent pain and medicine use was consistent across regions despite large inter-regional differences in the prevalence of both phenomena.

Conclusions: Recurrent pain in adolescence is common nationwide. Adolescents with recurrent pain are more likely to use medicines in general. Recurrent pain and medicine use should be addressed by adolescent health policies.

https://doi.org/10.15167/2421-4248/jpmh2019.60.4.1382
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References

1. World Health Organization. WHO – Recognizing adolescence. Available from: www.who.int/maternal_child_adolescent/topics/adolescence/development/en/
2. Holstein BE, Andersen A, Fotiou A, Gobina I, Godeau E, Holme Hansen E, Iannotti R, Levin K, Gabhainn SN, Ravens-Sieberer U, Valimaa R and the Medicine Use Writing Group. Adolescents’ medicine use for headache: secular trends in 20 countries from 1986 to 2010. Eur J Public Health. 2015;(25 Suppl 2):76-9.
3. Andersen A, Holstein BE, Hansen EH. Is medicine use in adolescence risk behavior? Cross-sectional survey of school-aged children from 11 to 15. J Adolesc Health. 2006;39(3):362-6.
4. Hansen, DL, Hansen EH, Holstein BE. Young women’s use of medicines: autonomy and positioning in relation to family and peer norms. Health (London). 2009;13(4):467-85.
5. Holstein BE, Holme Hansen E, Due P, Birna Almarsdottir A. Self-reported medicine use among 11- to 15-yearold girls and boys in Denmark 1988-1998. Scand J Public Health. 2003;31(5):334-41.
6. Levin KA, Whitehead R, Andersen A, Levin D, Gobina I, Holstein B. Changes in the association between health complaint frequency and medicine use among adolescents in Scotland between 1998 and 2010. J Psychosom Res. 2015;78(4): 371-6.
7. Gobina I, Valimaa R, Tynjala J, Villberg J, Villerusa A, Iannotti RJ, Godeau E, Gabhainn SN, Andersen A, Holstein BE, H.M.U.W. Group, Griebler R, Borup I, Kokkevi A, Fotiou A, Boraccino A, Dallago L, Wagener Y, Levin K, Kuntsche E. The medicine use and corresponding subjective health complaints among adolescents, a cross-national survey. Pharmacoepidemiol Drug Saf. 2011;20(4):424-31.
8. Gobina I, Villberg J, Villerusa A, Valimaa R, Tynjala J, Ottova-Jordan V, Ravens-Sieberer U, Levin K, Cavallo F, Borraccino A, Sigmund E, Andersen A, Holstein BE. Self-reported recurrent pain and medicine use behaviours among 15-year olds: results from the international study. Eur J Pain. 2015;19(1):77-84.
9. Hansen EH, Holstein BE, Due P, Currie CE. International survey of self-reported medicine use among adolescents. Ann Pharmacother. 2003;37(3):361-6.
10. Andersen A, Holstein BE, Due P, Hansen EH. Medicine use for headache in adolescence predicts medicine use for headache in young adulthood. Pharmacoepidemiol Drug Saf. 2009;18(7):619-23.
11. Lazzeri G, Giacchi MV, Dalmasso P, Vieno A, Nardone P, Lamberti A, Spinelli A, Cavallo F, H. Group, The methodology of the Italian HBSC 2010 study (Health Behaviour in School-aged Children). Ann Ig. 2013;25(3):225-33.
12. HBSC. Health Behavior in School-Aged Children. A World Health Organization Cross-National Study. Reasearch Protocol for the 2009/2010 survey. 2010. Available from: www.hbsc.org2010.
13. Roberts C, Freeman J, Sandal O, Schnohr CW, de Looze ME, Nic Gabhainn A, Iannotti R, Rasmussen M and the International HBSC Study Group. The Health Behaviour in School-aged Children (HBSC) study: methodological developments and current tensions. Int J Public Health. 2009;54(Suppl 2):140-50.
14. Austin PC, Merlo J, 2017, Intermediate and advanced topics in multilevel logistic regression analysis, Statistics in medicine, 36:3257-3277.
15. Holstein BE. Hansen EH, Due P. Social class variation in medicine use among adolescents. Eur J Public Health. 2004;14(1):49-52.
16. Koushede V. Holstein BE. Sense of coherence and medicine use for headache among adolescents. J Adolesc Health. 2009;45(2):149-55.
17. Haugland S, Wold B, Stevenson J, Aaroe LE, Woynarowska B. Subjective health complaints in adolescence. A cross-national comparison of prevalence and dimensionality. Eur J Public Health. 2001;11(1):4-10.
18. Roth-Isigkeit A, Thyen U, Raspe HH,Stoven H, Schmucker P. Reports of pain among German children and adolescents: an epidemiological study. Acta Paediatr. 2004;93(2):258-63.
19. Torsheim T, Ravens-Sieberer U, Hetland J, Valimaa R, Danielson M, M. Overpeck M. Cross-national variation of gender differences in adolescent subjective health in Europe and North America. Soc Sci Med. 2006;62(4):815-27.
20. Gobina I1, Villberg J, Villerusa A, Välimaa R, Tynjälä J, Ottova-Jordan V, Ravens-Sieberer U, Levin K, Cavallo F, Borraccino A, Sigmund E, Andersen A, Holstein BE. Self-reported recurrent pain and medicine use behaviours among 15-year olds: results from the international study.Eur J Pain. 2015 Jan;19(1):77-84. doi: 10.1002/ejp.524. Epub 2014 May 8.
21 Trombetta Claudia Maria, Manini Ilaria, Pammolli Andrea, Stefania Rossi, Teresa Pozzi, Emanuele Montomoli, Giacomo Lazzeri. Medicine use and recurrent complaints among 15-years-old adolescents in Tuscany. Ann Ist Super Sanità 2018 Vol. 54, No. 3: 208-213
22. Fitchel & Larsson, 2002 Psychosocial Impact of Headache and Comorbidity with Other Pains among Swedish School Adolescents (Headache.2002;42:766-775)
23. Gualano MR, Bert F, Passi S, Stillo M, Galis V, Manzoli L, Siliquini R. Use of self-medication among adolescents: a systematic review and meta-analysis. Eur J Public Health. 2015;25(3):444-50.
24. Roth‐Isigkeit, A., Thyen, U., Stőven, H., Schwarzenberger, J., Schmucker, P.(2005). Pain among children and adolescents: Restriction in daily living and triggering factors. Pediatrics 115, e152–e162.
25. Powers, S.W., Gilman, D.K., Hershey, A.D. (2006). Headache and psychological functioning in children and adolescents. Headache 46, 1404–1415.
26. Gauntlett‐Gilbert, J., Eccleston, C. (2007). Disability in adolescents with recurrent pain: Patterns and predictors across different domains of functioning. Pain 13, 132–141.
27. Larsson, B., Sund, A.M. (2007). Emotional/behavioural, social correlates and one‐year predictors of frequent pains among early adolescents: Influences of pain characteristics. Eur J Pain 11, 57–65.
28. Waldie, K.E. (2011). Childhood headache, stress in adolescence, and primary headache in young adulthood: A longitudinal cohort study.Headache 41, 1–10.