Keywords
occupational disease
risk factors
chemical hazards
exposure
Abstract
Introduction: Exposure with some chemical can cause cardiovascular disorders. Occupational exposures with chemicals are modifiable risk factors for cardiovascular diseases.
Objective of this study was the frequency of cardiovascular disorders in the chemical exposure.
Materials and Methods: Study was a cross-sectional method and was done on workers of related industries. The study was done with a physical examination and checklist by getting health and illness history and clinical tests about the risk factors and cardiovascular disorders. According to exposures the population of the study was divided into 3 groups. Data were analyzed with SPSS 16, by considering P<0.05 as significant.
Results: The frequency of unstable angina and stable angina were the most in group 1. The relative risk for unstable angina was 1.55(1.46-1.61) in group 1 and for stable angina was 1.54(1.47-1.62) in this group. The risk of thrombophlebitis was 8.48 (7.07-10.17) in group 2.
Conclusion: Workers in industry with chemical pollutants had cardiovascular disorders. The occupational exposures, especially chemical agents are effective on cardiovascular system.
References
REFERENCES
Global status report on non communicable diseases report, World health organization,2021 , WHO,online:[ HTTP:// www.who.int]
Risk factors, world heart federation. 2019,WHF, online:[https://www. world-heart-federation.org /resources/risk-factors]
Price A.E,Petch M.C, Cardiovascular disorders, In: Palmer K.T,Cox R.A.F,Brown I, Fitness for work The medical aspects.The Oxford university press .2007;4th ed: 381-400. online: [https://www.books.google.com]
Rosenman K.D, Occupational heart disease, In: Rom W.N, Environmental and Occupational Medicine. The Lippincott Williams and Wilkins. 2007 ;4th ed: 681-93. online: [https://www.books.google.com]
Lead: health problems caused by lead,CDC,2018, online: [http://www.cdc.gov/niosh]
Ibfelt E, Bonde JP, Hansen J. Exposure to metal welding fume particles and risk for cardiovascular disease in Denmark: a prospective cohort study. Occup Environ Med. 2010;67:772-77. doi: 10.1136/oem.2009.051086. Epub 2010 Jun 27.
Bushnik T, Levallois P, D'Amour M, Anderson TJ, McAlister FA, Association between blood lead and blood pressure: Results from the Canadian Health Measures Survey(2007 to 2011). Health Rep. 2014;25:12-22. https://pubmed.ncbi.nlm.nih.gov/25029492/
Mannocci A, Pignalosa S, Saulle R, Sernia S, De Sanctis S, Consentino M, Gialdi C, Nicosia V, La Torre G.Prevalence of major cardiovascular risk factors among oil and gas and energy company workers. Ann Ist Super Sanita. 2015;51(2):148-53. doi: 10.4415/ANN_15_02_13.
Picciotto S, Peters A, Eisen EA. Hypothetical exposure limits for oil-based metalworking fluids and cardiovascular mortality in a cohort of autoworkers: structural accelerated failure time models in a public health framework. Am J Epidemiol. 2015 15;181(8):563-70. doi: 10.1093/aje/kwu484. Epub 2015 Mar 27.
Plat MJ, Frings-Dresen MH, Sluiter JK. Diminished health status in firefighters. Ergonomics. 2012;55:1119-22. doi: 10.1080/00140139.2012.697581. Epub 2012 Jul 17.
Kersten N, Backé E. Occupational noise and myocardial infarction: considerations on the interrelation of noise with job demands. Noise Health. 2015;17(75):116-22. doi: 10.4103/1463-1741.153403.
Kreuzer M, Auvinen A, Cardis E, Hall J, Jourdain JR, Laurier D, Little MP, Peters A, Raj K, Russell NS, Tapio S, Zhang W, Gomolka M. Low-dose ionizing radiation and cardiovascular diseases - Strategies for molecular epidemiological studies in Europe. Mutat Res Rev Mutat Res. 2015;764:90-100. doi: 10.1016/j.mrrev.2015.03.002.
Assunta C, Ilaria S, Simone de S, Gianfranco T, Teodorico C, Carmina S, Anastasia S, Roberto G, Francesco T, Valeria RM.Noise and cardiovascular effects in workers of the sanitary fixtures industry. Int J Hyg Environ Health. 2015;218(1):163-68. doi: 10.1016/j.ijheh.2014.09.007. Epub 2014 Oct 27.
Foraster M, Künzli N, Aguilera I, Rivera M, Agis D, Vila J. Bouso L, Deltell A, Marrugat J, Ramos R, Sunyer J, Elosua R, Basagaña X.High Blood Pressure and Long-Term Exposure to Indoor Noise and Air Pollution from Road Traffic. Environ Health Perspect. 2014. 122:1193-200. doi: 10.1289/ehp.1307156. Epub 2014 Jul 8.
Tuo B, Li C, Peng L, Ye M, Liu W, Zhong X, Li H, Analysis of differentially expressed genes in cold-exposed mice to investigate the potential causes of cold-induced hypertension. Exp Ther Med. 2014;8:110-114. doi: 10.3892/etm.2014.1703. Epub 2014 May 8.
Koskinen HL, Kauppinen T, Tenkanen L.Dual role of physical workload and occupational noise in the association of the metabolic syndrome with the risk of coronary heart disease: findings from the Helsinki Heart Study. Occup Environ Med. 2011;68:666-73. doi: 10.1136/oem.2010.057075
Martino TA, Young ME. Influence of the Cardiomyocyte Circadian Clock on Cardiac Physiology and Pathophysiology. J Biol Rhythms. 2015;30(3):183-205. doi: 10.1177/0748730415575246.
Alibhai FJ, Tsimakouridze EV, Reitz CJ, Pyle WG, Martino TA. Consequences of Circadian and Sleep Disturbances for the Cardiovascular System. Can J Cardiol. 2015;31(7):860-72. doi: 10.1016/j.cjca.2015.01.015. Epub 2015 Jan 26.
Park S, Nam J, Lee JK, Oh SS, Kang HT, Koh SB. Association between night work and cardiovascular diseases: analysis of the 3rd Korean working conditions survey. Ann Occup Environ Med. 2015 May 11;27:15. doi: 10.1186/s40557-015-0064-1. collection 2015. doi: 10.1186/s40557-015-0064-1. eCollection 2015.
Silva-Costa A, Griep RH, Rotenberg L. Disentangling the effects of insomnia and night work on cardiovascular diseases: a study in nursing professionals. Braz J Med Biol Res. 2015 48(2):120-7. doi: 10.1590/1414-431X20143965. Epub 2014 Nov 21.
Lajoie P, Aronson KJ, Day A, Tranmer J.A cross-sectional study of shift work, sleep quality and cardiometabolic risk in female hospital employees. BMJ Open. 2015 10;5(3):e007327. doi: 10.1136/bmjopen-2014-007327.
Yong M, Germann C, Lang S, Oberlinner C Primary selection into shift work and change of cardiovascular risk profile. Scand J Work Environ Health. 2015 1;41(3):259-67. doi: 10.5271/sjweh.3487. Epub 2015 Feb 20.
Pimenta AM, Kac G, Souza RR, Ferreira LM, Siqueira SM, Night-shift work and cardiovascular risk among employees of a public university. Rev Assoc Med Bras. 2012;58:168-77. https://pubmed.ncbi.nlm.nih.gov/22569611/
Juárez-Pérez CA, Aguilar-Madrid G, Haro-García LC, Gopher-Nieto R, Cabello-López A, Jiménez-Ramírez C, Aguado A, Martínez-Méndez LM, Chávez-Negrete A. Increased Cardiovascular Risk Using Atherogenic Index Measurement Among Healthcare Workers. Arch Med Res. 2015;46(3):233-39. doi: 10.1016/j.arcmed.2015.03.002. Epub 2015 Mar 19.
Ohlander J, Keskin MC, Stork J, Radon K. Shift work and hypertension: Prevalence and analysis of disease pathways in a German car manufacturing company. Am J Ind Med. 2015;58(5):549-60. doi: 10.1002/ajim.22437. Epub 2015 Mar 13.
Mirmohammadi SJ, Taheri M, Mehrparvar AH, Heydari M, Saadati Kanafi A, Mostaghaci M. Occupational stress and cardiovascular risk factors in high-ranking government officials and office workers. Iran Red Crescent Med J. 2014;16(8):e11747 doi: 10.5812/ircmj.11747. Epub 2014 Aug 1.
Maeda E, Iwata T, Murata K. Effects of work stress and home stress on autonomic nervous function in Japanese male workers. Ind Health. 2015;53(2):132-38. doi: 10.2486/indhealth.2014-0157. Epub 2014 Nov 8.
Babu GR, Jotheeswaran AT, Mahapatra T, Mahapatra S, Kumar A Sr, Detels R, Is hypertension associated with job strain? A meta-analysis of observational
Studies. Postgrad Med J. 2014;90:402-409. doi: 10.1136/postgradmedj-2013-101396rep.
Babu GR, Mahapatra T, Detels R. Job stress and hypertension in younger software professionals in India.Indian J Occup Environ Med. 2013;17:101-107. doi: 10.4103/0019-5278.130848.
Kruk ME, Nigenda G, Knaul FM. Redesigning primary care to tackle the global epidemic of noncommunicable disease. Am J Public Health. 2015;105(3):431-37. doi: 10.2105/AJPH.2014.302392. Epub 2015 Jan 20.
Polvinen A, Laaksonen M, Gould R, Lahelma E, Leinonen T, Martikainen P. Socioeconomic inequalities in cause-specific mortality after disability retirement due to different diseases. Scand J Public Health. 2015;43(2):159-68. doi: 10.1177/1403494814562597. Epub 2014 Dec 10
Gao J, Liang X, Shi J, Huang Z, Wei X, Li H, Lin L, Xing A, Du X, Wu S. Impact of ideal cardiovascular health behaviors and factors on resting heart rate in individuals without cardiovascular diseases. Zhonghua Xin Xue Guan Bing Za Zhi. 2014;42(9):778-83. https://pubmed.ncbi.nlm.nih.gov/25511100/
López-González ÁA, Bennasar-Veny M, Tauler P, Aguilo A, Tomàs-Salvà M, Yáñez A.Socioeconomic inequalities and age and gender differences in cardiovascular risk factors. Gac Sanit. 2015;29(1):27-36. doi: 10.1016/j.gaceta.2014.08.004.
Tao J, Li D, Dong Y, Wu S.Relationship between resting heart rate and brachial-ankle pulse wave velocity in a healthy Chinese population. Zhonghua Xin Xue Guan Bing Za Zhi. 2014;42(8):686-92. https://pubmed.ncbi.nlm.nih.gov/25388344/
Akintunde AA, Salawu AA, Opadijo OG. Prevalence of traditional cardiovascular risk factors among the staff of Ladoke Akintola University of Technology, Ogbomoso, Nigeria. Niger J Clin Pract. 2014 17(6):750-55. doi: 10.4103/1119-3077.144390.
Jagannathan R, Nanditha A, Sundaram S, Simon M, Shetty AS, Snehalatha C, Johnston
DG, Ramachandran A. Screening among male industrial workers in India shows a high prevalence of impaired glucose tolerance, undetected diabetes, and cardiovascular risk clustering. J Assoc Physicians India. 2014;62(4):312-15. https://pubmed.ncbi.nlm.nih.gov/25327033/
Ogedegbe G, Gyamfi J, Plange-Rhule J, Surkis A, Rosenthal DM, Airhihenbuwa C, Iwelunmor J, Cooper R.Task shifting interventions for cardiovascular risk reduction in low-income and middle-income countries: a systematic review of randomized controlled trials. BMJ Open. 2014;4(10):e005983. doi: 10.1136/bmjopen-2014-005983.
Lin CM, Li CY. Prevalence of cardiovascular risk factors in Taiwanese healthcare workers. Ind Health. 2009;47:411–18. doi: 10.2486/indhealth.47.411.
Santini A, Caciari T, De Sio S, Fiaschetti M, Di Giorgio V, Samperi I, et al. Cardiovascular diseases in workers at risk. G Ital Med Lav Ergon. 2010;32:163–65. https://pubmed.ncbi.nlm.nih.gov/21438249/
Kang K, Koh SB, Cha BS, Park JK, Baik SK, Chang SJ. Job stress and cardiovascular risk factors in male workers. Prev Med. 2005;40:583–88. doi: 10.1016/j.ypmed.2004.07.018.
Rijs KJ, van der Pas S, Geuskens GA, Cozijnsen R, Koppes LL, van der Beek AJ,
Deeg DJ. Development and validation of a physical and psychosocial job-exposure matrix in older and retired workers. Ann Occup Hyg. 2014;58:152-70. doi: 10.1093/annhyg/met052. Epub 2013 Nov 4.
NIOSH recommended standards, national institute for occupational safety and health,2021, online:[https:// www.cdc.gov/niosh ]