Keywords
RTS S/AS01, malaria, plasmodium, developing countries, endemic
Abstract
The paper puts spotlight on the new malarial vaccine RTS S/AS01 that can play a groundbreaking role in controlling malaria in the malarial endemic countries where a large portion of the native population suffers from this deadly infectious disease or its complications. Owing to a large number of morbidity and mortality cases as a consequence of malaria, we propose a trial run of RTS S/AS01 supervised by WHO in Pakistan, a developing country which still struggles to combat malaria to this date.
References
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[2]: Nussenzweig RS, Vanderberg J, Most H, Orton C. Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei. Nature. 1967;216(5111):160–162.
[3]:https://www.who.int/news-room/q-a-detail/q-a-on-rts-s-malaria-vaccine
World Health Organization. Q&A on RTS,S malaria vaccine [Internet]. 2021 [cited 27 October 2021]. Available from: https://www.who.int/news-room/q-a-detail/q-a-on-rts-s-malaria-vaccine
[4]: Durrani, N. (1997/09/01). Chloroquine resistance in Pakistan and the upsurge of falciparum malaria in Pakistani and Afghan refugee populations. Annals of Tropical Medicine & Parasitology, 91, 591-602. doi: 10.1080/00034983.1997.11813177. Available from: https://www.tandfonline.com/doi/abs/10.1080/00034983.1997.11813177
[5]:Kondrashin AV, Baranova AM, Morozov EN, Morozova LF, Stepanova EV. [The current status of the resistance of malaria pathogens to antimalarials]. Med Parazitol (Mosk). 2014 Jul-Sep;(3):51-7. Russian. PMID: 25286554.
[2]: Nussenzweig RS, Vanderberg J, Most H, Orton C. Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei. Nature. 1967;216(5111):160–162.
[3]:https://www.who.int/news-room/q-a-detail/q-a-on-rts-s-malaria-vaccine
World Health Organization. Q&A on RTS,S malaria vaccine [Internet]. 2021 [cited 27 October 2021]. Available from: https://www.who.int/news-room/q-a-detail/q-a-on-rts-s-malaria-vaccine
[4]: Durrani, N. (1997/09/01). Chloroquine resistance in Pakistan and the upsurge of falciparum malaria in Pakistani and Afghan refugee populations. Annals of Tropical Medicine & Parasitology, 91, 591-602. doi: 10.1080/00034983.1997.11813177. Available from: https://www.tandfonline.com/doi/abs/10.1080/00034983.1997.11813177
[5]:Kondrashin AV, Baranova AM, Morozov EN, Morozova LF, Stepanova EV. [The current status of the resistance of malaria pathogens to antimalarials]. Med Parazitol (Mosk). 2014 Jul-Sep;(3):51-7. Russian. PMID: 25286554.