The possible impact of SARS-COV-2 (COVID-19) on neglected tropical diseases in Europe: the out of spotlights emerging of schistosomiasis.


neglected diseases
tropical diseases
history of tropical disease


SARS-COV-2 (COVID-19) pandemic is a serious threat to health care around the world and yet little is known about how COVID-19 is impacting the millions of people worldwide with neglected diseases. Especially in the last decades, Europe is facing a slow increasing incidence of neglected tropical diseases that were previously considered as uncommon. In particular, schistosomiasis is one of the neglected parasitic infective urological diseases which is increasingly being reported in healthcare facilities in Europe. Until a few years ago, urogenital schistosomiasis was not endemic in Europe and it is underreported disease that can certainly be defined as neglected.

SARS-CoV-2 and Schistosomiasis, now, represent a possible threat to each other. Furthermore, the pandemic with its disruptive effect can further lead to a reduction in attention towards schistosomiasis. Precise strategies and implementation of recent guidelines are therefore needed to improve early diagnosis.


1 – Costantino C, Fiacchini D. Rationale of the WHO document on Risk Communication and Community Engagement (RCCE) readiness and response to the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and of the Italian Decalogue for Prevention Departments. J Prev Med Hyg. 2020 Apr 2;61(1):E1-E2.
2 - Mantica G, Van der Merwe A, Bonkat G. Greetings from Africa: The Emergence of Tropical Urological Diseases in Europe. We Had Better Be Prepared! Eur Urol. 2019 Aug;76(2):140-141.
3 – Di Bella S, Riccardi N, Giacobbe DR, Luzzati R. History of schistosomiasis (bilharziasis) in humans: from Egyptian medical papyri to molecular biology on mummies. Pathog Glob Health. 2018 Jul;112(5):268-273.
4 – Boissier J, Grech-Angelini S, Webster BL, Allienne JF, Huyse T, Mas-Coma S, Toulza E, Barré-Cardi H, Rollinson D, Kincaid-Smith J, Oleaga A, Galinier R, Foata J, Rognon A, Berry A, Mouahid G, Henneron R, Moné H, Noel H, Mitta G. Outbreak of urogenital schistosomiasis in Corsica (France): an epidemiological case study. Lancet Infect Dis. 2016 Aug;16(8):971-9.
5 – Comelli A, Riccardi N, Canetti D, Spinicci M, Cenderello G, Magro P, Nicolini LA, Marchese V, Zammarchi L, Castelli F, Bartoloni A, Di Biagio A, Caligaris S, Gaiera G. Delay in schistosomiasis diagnosis and treatment: a multicenter cohort study in Italy. J Travel Med. 2020 Feb 3;27(1):taz075.
6 - Salas-Coronas J, Vázquez-Villegas J, Lozano-Serrano AB, Soriano-Pérez MJ, Cabeza-Barrera I, Cabezas-Fernández MT, Villarejo-Ordóñez A, Sánchez-Sánchez JC, Abad Vivas-Pérez JI, Vázquez-Blanc S, Palanca-Giménez M, Cuenca-Gómez JA. Severe complications of imported schistosomiasis, Spain: A retrospective observational study. Travel Med Infect Dis. 2020 May-Jun;35:101508.
7 - Janda A, Eder K, Fressle R, Geweniger A, Diffloth N, Heeg M, Binder N, Sitaru AG, Rohr J, Henneke P, Hufnagel M, Elling R. Comprehensive infectious disease screening in a cohort of unaccompanied refugee minors in Germany from 2016 to 2017: A cross-sectional study. PLoS Med. 2020 Mar 31;17(3):e1003076.
8 - Gulyás K, Soldánová M, Orosová M, Oros M. Confirmation of the presence of zoonotic Trichobilharzia franki following a human cercarial dermatitis outbreak in recreational water in Slovakia. Parasitol Res. 2020 Aug;119(8):2531-2537.
9 - Mantica G, Van der Merwe A, Terrone C, Gallo F, Zarrabi AD, Vlok AL, Ackermann HM, Territo A, Esperto F, Olapade-Olapa EO, Riccardi N, Bongers M, Bonkat G. Awareness of European practitioners toward uncommon tropical diseases: are we prepared to deal with mass migration? Results of an international survey. World J Urol. 2020 Jul;38(7):1773-1786.